The global burden of ischemic heart disease is burgeoning for both men and women.Although advances have been made, the need for new sex-specific therapies targeting key differences in cardiovascular disease outcomes in men and women remains.Mineralocorticoid receptor directed treatments have been successfully used for blood pressure control and hea
Background: The Indiana University Center for Global Health coined the term reciprocal innovation to describe bidirectional, mutually beneficial research and translational research within long-term global health partnerships.Inspired by a 30-year global health partnership between Indiana University (Indianapolis, IN, USA) and Moi University College
Abstract ISG15, an interferon-stimulated ubiquitin-like protein, plays a multifaceted role in tumorigenesis and immune regulation.This study comprehensively evaluates ISG15 as a prognostic biomarker and predictor of immunotherapy response through pan-cancer bioinformatics analysis and experimental validation.By integrating multiomics data from TCGA